Antifungal Susceptibility and Stress Tolerance of 196 Talaromyces Marneffei Strains

196 Talaromyces marneffei strains were assessed for antifungal susceptibility against nine agents and stress adaptability under four conditions. The dataset compares clinical isolates from HIV-positive and HIV-negative patients with non-clinical strains. Kai-Su Pan authored the study, which was last updated on 2026-05-05.

Use Cases

• Compare antifungal drug efficacy based on MIC values for nine antifungal agents.
• Analyze differences in environmental stress tolerance between clinical and non-clinical fungal strains.
• Investigate phenotypic adaptations linked to host infection based on growth under KCl, Congo red, H2O2, and Calcofluor white stress.
• Model associations between host adaptation factors and antifungal susceptibility independent of HIV status or patient age.

Strengths

• Includes data on 196 distinct fungal strains.
• Compares two distinct strain groups: 20 clinical and 20 non-clinical isolates for stress tests.
• Assesses susceptibility against nine specific antifungal agents.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale at 23.5 KB.

Provenance

Source

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Collection Method

Broth microdilution and Sensititre YeastOne YO10 methods were used to determine MICs; stress adaptability was evaluated via colony growth under specific stressors.

Freshness

Last updated 2026-05-05 05:24:03; freshness should be verified.

Geography

Southeast Asia (implied by disease prevalence).