Clinical Utility of a Host-Protein Test in Pediatric Emergency Departments

1,496 pediatric patient records compare antibiotic prescribing rates before and after implementing the MeMed BV host-protein test. The retrospective study from a single center shows a significant reduction in antibiotic use for viral infections and a shorter hospital length of stay. The dataset, authored by Vered Nir and licensed CC-BY-4.0, was last updated in May 2026.

Use Cases

• Evaluate the impact of a diagnostic test on clinical decision-making based on the pre-/post-implementation study design.
• Analyze changes in antibiotic prescribing patterns based on patient disposition and test results described in the study.
• Model the relationship between diagnostic test availability and hospital length of stay based on the reported patient outcomes.

Strengths

• Includes 1,022 patients in the standard care arm and 474 in the intervention arm, providing a basis for comparison.
• Reports statistically significant results, such as a reduction in antibiotic prescribing from 20.3% to 7.5% for outpatients with viral test results.
• Examines multiple endpoints including prescribing rates in a lower respiratory tract infection subcohort and hospital length of stay.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is from a single-center study, which may limit generalizability.

Provenance

Source

figshare

Collection Method

Retrospective analysis of two pragmatic cohort studies at a single pediatric emergency department.

Freshness

Last updated 2026-05-15 05:40:56; freshness should be verified.