HIV, Coagulation, and Kidney Function Data from a South African Cross-Sectional Study

151 adult participants from a cross-sectional study investigating associations between coagulation markers and renal function decline in people living with HIV (PLWH). The dataset likely contains measurements of inflammatory and coagulation markers (C-reactive protein, fibrinogen, D-dimer) and kidney function estimates (eGFR based on cystatin C) for PLWH on ART, PLWH not on ART, and people not living with HIV. Joel Choshi authored the study, which was last updated on figshare in May 2026.

Use Cases

• Analyze associations between coagulation markers (D-dimer, fibrinogen) and kidney function decline based on eGFRcystC measurements.
• Compare renal function and biomarker levels between PLWH on ART, PLWH not on ART, and HIV-negative controls.
• Model the risk of chronic kidney disease (CKD) based on elevated fibrinogen or D-dimer levels.
• Investigate whether coagulation activation serves as an early indicator of declining kidney function in PLWH.

Strengths

• Includes 151 participants from three distinct cohorts (PLWH on ART, PLWH not on ART, HIV-negative controls).
• Key biomarker measurements (C-reactive protein, fibrinogen, D-dimer) and kidney function estimates (eGFRcystC) are described.
• Statistical associations (p-values, odds ratios) between coagulation markers and renal outcomes are reported in the description.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is 16.4 KB, indicating a very limited scope.

Provenance

Source

figshare

Collection Method

Cross-sectional study with 151 adult participants.

Freshness

Last updated 2026-05-22 05:34:38; freshness should be verified.

Geography

South Africa