Cognitive Outcomes After Endovascular Thrombectomy in Ischemic Stroke: A Systematic Review

Twenty-three studies involving approximately 3,300 participants were synthesized to assess the impact of endovascular thrombectomy on cognition. The review, conducted by Wiktoria Balcerzak and published in 2026, found EVT was associated with better cognitive outcomes than intravenous thrombolysis or best medical therapy. Benefits were most consistent in executive functions, though post-stroke cognitive impairment remained frequent.

Use Cases

• Summarizing evidence on cognitive benefits of endovascular thrombectomy based on the review of 23 studies.
• Identifying factors linked to worse cognitive outcomes based on reported associations with infarct volume and time to reperfusion.
• Informing the design of future clinical trials based on the identified need for standardized cognitive assessment and longer-term follow-up.

Strengths

• Follows PRISMA 2020 guidelines for systematic review methodology.
• Includes data from approximately 3,300 participants across 23 studies.
• Explicitly registered with PROSPERO (CRD420251156363).

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• Quantitative meta-analysis was not feasible due to substantial heterogeneity in assessment tools and outcome definitions.

Provenance

Source

figshare

Collection Method

Systematic review of randomized controlled trials and observational studies from PubMed, Embase, Cochrane Library, and Scopus.

Time Range

Studies published from 1 January 2015 to 31 October 2025.

Freshness

Last updated 2026-05-11 05:28:18; freshness should be verified.