Table 1_Comparative study of targeted next-generation sequencing and traditional pathogen

562 patients with suspected lower respiratory infections were enrolled from 29 departments during 2023–2025. This retrospective study compares targeted next-generation sequencing (tNGS) to conventional microbiological tests, reporting detection rates and clinical outcomes. The dataset was authored by Zhengyuan An and last updated in May 2026.

Use Cases

• Compare pathogen detection rates between tNGS and conventional methods based on the reported primary outcomes.
• Analyze the impact of diagnostic-guided therapy on hospital stay length and mortality based on the adjusted regression results.
• Investigate antibiotic modification rates following tNGS results based on the secondary outcome described.
• Assess the sensitivity of different diagnostic methods for special pathogens, viruses, and fungi based on the comparative statistics.

Strengths

• Includes results from 562 patients, providing a substantial clinical sample size.
• Reports specific, statistically significant findings such as an 89.5% pathogen detection rate for tNGS versus 62.1% for CMTs.
• Study design incorporates multivariable logistic regression and propensity score adjustment for outcome analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 18.3 KB file size suggests the dataset is a summary document, not the raw underlying data.

Provenance

Source

Zhengyuan An

Collection Method

Retrospective study analyzing bronchoalveolar lavage fluid samples tested with parallel tNGS and conventional methods.

Time Range

2023–2025

Freshness

Last updated 2026-05-08 05:52:32; freshness should be verified.

Geography

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