Canine Cerebrovascular Accident Blood Count Markers for Diagnostic and Prognostic Use

A retrospective study of 17 dogs with MRI-confirmed cerebrovascular accidents (CVA) and 20 healthy controls, authored by Seungkuk Oh and last updated in April 2026. It evaluates the diagnostic and prognostic utility of inflammatory markers derived from complete blood counts. The dataset includes calculated neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) values, functional outcome scores, and 30-day survival data.

Use Cases

• Differentiating dogs with CVA from healthy controls based on neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) values.
• Predicting short-term (30-day) survival outcomes in canine CVA patients using the SII biomarker.
• Assessing correlations between inflammatory markers and functional recovery scores (CFSS) mentioned in the study.
• Evaluating the performance of optimal biomarker cutoffs (e.g., NLR 3.92, SII 1,352) for clinical decision support.

Strengths

• Includes data from 37 subjects (17 cases, 20 controls) for comparative analysis.
• Provides specific diagnostic performance metrics, including AUC values of 0.82 for NLR and 0.85 for SII.
• Reports optimal clinical cutoffs with sensitivity and specificity figures (e.g., 70.6% and 90.0% for NLR).
• Links biomarker levels to 30-day survival and functional outcomes, offering prognostic insights.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (31.1 KB), indicating a limited scope and sample size.

Provenance

Source

figshare

Collection Method

Retrospective analysis of medical records from dogs with MRI-confirmed CVA and healthy controls.

Freshness

Last updated 2026-04-22 07:23:13; freshness should be verified.