Copper and Cuproptosis Gene Expression for Traumatic Brain Injury Time Estimation

Rui Gu's research dataset on figshare, last updated 2026-05-29, investigates biomarkers for estimating the time since traumatic brain injury. The data likely contains gene expression levels for FDX1, DLD, SLC31A1, and LIAS from human postmortem and mouse model samples. Findings suggest these markers correlate with injury progression within 30 days post-TBI.

Use Cases

• Training models to estimate early-stage TBI time based on FDX1, DLD, and SLC31A1 expression levels.
• Developing classifiers for late-stage TBI injury time using LIAS and SLC31A1 expression.
• Studying the correlation between copper ion content and time-dependent progression of cerebral contusion.
• Validating cuproptosis pathway activation as a biomarker in animal models of traumatic brain injury.

Strengths

• Data is derived from both human postmortem samples and prospective mouse TBI models, providing cross-species validation.
• The study specifies a clear 30-day observation window for human TBI progression.
• License is CC-BY-4.0, permitting open sharing and adaptation.

Limitations

• The dataset is very small at 19.4 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Rui Gu via figshare.

Collection Method

Retrospective detection of human postmortem samples and prospective experiments on mouse TBI models.

Time Range

Observations within 30 days post-TBI onset in humans.

Freshness

Last updated 2026-05-29 04:53:54; freshness should be verified.