EAT Thickness and Cognitive Scores in 99 Older Italian Adults

99 participants aged over 65 underwent echocardiography, 24-hour Holter ECG monitoring, and MMSE cognitive assessment. The dataset contains clinical measurements exploring the correlation between Epicardial Adipose Tissue thickness and cognitive performance. It includes Heart Rate Variability metrics like SDNN and LF/HF ratio as potential explanatory variables.

Use Cases

• Analyze the inverse correlation between EAT thickness and MMSE scores using the reported Spearman's rho (ρ = −0.341).
• Investigate the association of EAT thickness with the SDNN index of Heart Rate Variability (ρ = 0.212).
• Compare EAT thickness and LF/HF ratio between dementia and mild cognitive impairment groups.
• Perform multivariate analysis to test if EAT thickness predicts MMSE scores after adjusting for age, sex, BMI, and HRV metrics.

Strengths

• Data from 99 clinically evaluated participants at a university hospital outpatient clinic.
• Includes multiple validated clinical measures: EAT thickness from echocardiography, HRV from 24-hour Holter, and MMSE for cognitive status.
• Multivariate analysis results are provided, adjusting for key confounders like age, sex, and BMI.

Limitations

• Small cohort size of 99 participants limits statistical power and generalizability.
• Sample is geographically limited to patients from a single hospital in Italy.
• Data is presented in a research paper (DOCX), not in a structured, machine-readable tabular format.

Provenance

Source

Martina Valentino, Federico II University Hospital.

Collection Method

Participants enrolled at outpatient clinics and underwent transthoracic echocardiography, 24-hour Holter ECG monitoring, and MMSE cognitive assessment.

Time Range

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Freshness

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Geography

Italy (Federico II University Hospital).