Post-COVID-19 Fatigue Creatine Supplementation Trial Results

67 individuals were randomized in a single-blind, placebo-controlled pilot study investigating creatine supplementation for post-COVID-19 condition fatigue. The dataset contains results for 58 participants who completed the 4-week protocol, with measurements including Piper Fatigue Scale scores, handgrip strength, body composition, and quality of life questionnaires. The study found a significant improvement in fatigue scores for the 6 g/day creatine group.

Use Cases

• Analyze the difference-in-differences in Piper Fatigue Scale scores before and after intervention across the 6 g/day, 18 g/day, and placebo groups.
• Assess the relationship between creatine dosage and changes in handgrip strength measurements among participants.
• Compare body composition analysis results and physical capacity test outcomes between intervention arms.
• Evaluate quality of life, dyspnea, anxiety, and depression questionnaire responses pre- and post-intervention.

Strengths

• Data originates from a randomized, single-blind, placebo-controlled pilot study, a rigorous experimental design.
• Includes results from 58 participants who completed the full 4-week intervention protocol.
• Measures multiple outcomes: fatigue scores, muscle strength, body composition, lung function, and psychological questionnaires.

Limitations

• Small sample size of 67 randomized individuals limits statistical power and generalizability.
• Data is contained within a DOCX file, requiring manual extraction for computational analysis.
• The study is a pilot trial, indicating preliminary findings that require validation in larger studies.

Provenance

Source

Maercio Souza Cícero dos Santos via figshare

Collection Method

Randomized controlled trial with physical examinations, lab tests, pulmonary function tests, muscle ultrasound, strength assessments, body composition analysis, physical capacity tests, and questionnaires.

Time Range

Intervention period of 4 weeks.

Freshness

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Geography

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