Rabbit Milk Fat Globule Membrane Proteins, Colostrum vs. Mature Milk

3,548 milk fat globule membrane proteins identified across rabbit colostrum and mature milk. The dataset includes 480 differentially expressed proteins and functional annotations from GO and KEGG analyses. Liangde Kuang published the data on figshare in March 2026.

Use Cases

• Identify differentially expressed proteins between colostrum and mature milk based on the 480 DEMPs.
• Analyze protein functional profiles based on GO terms for proteolysis, cell adhesion, and ion transport.
• Investigate protein-protein interaction networks based on the PPI analysis mentioned.
• Validate specific MFGM protein markers (e.g., PLIN2, XDH/XO) using the 10 proteins confirmed by PRM.
• Explore pathway enrichment in human diseases and metabolism based on the 56 significant KEGG pathways.

Strengths

• Identifies 3,548 proteins, providing a broad proteomic profile.
• Quantifies 480 differentially expressed proteins with specific counts (379 up, 101 down).
• Includes functional validation for 10 proteins via Parallel Reaction Monitoring.
• Provides pathway analysis with 56 significant KEGG pathways categorized.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect bias inherent to the specific experimental and analytical methods used.

Provenance

Source

figshare

Collection Method

Data-independent acquisition (DIA) quantitative proteomics analysis.

Freshness

Last updated 2026-03-19 14:37:30; freshness should be verified.