Dedifferentiated Liposarcoma Case Report with Cytopathological and Molecular Analysis

A 19.1 KB case report authored by JingJun Wang details a 63-year-old female patient with dedifferentiated liposarcoma (DDLPS) presenting with ascites. The report, last updated in May 2026, integrates cytopathological, immunohistochemical, and fluorescence in situ hybridization (FISH) findings for diagnosis. It is one of the few documented cases where DDLPS initially manifested with malignant cells detected in peritoneal fluid.

Use Cases

• Studying diagnostic challenges of sarcomas presenting with serosal effusions based on the case description
• Analyzing the role of MDM2 gene amplification via FISH in sarcoma diagnosis as highlighted in the report
• Reviewing the integration of cytopathological and molecular testing for accurate tumor classification as described

Strengths

• Report includes specific diagnostic methods: immunohistochemical staining and FISH analysis for MDM2 amplification.
• Case details a rare clinical presentation (ascites as initial manifestation) of dedifferentiated liposarcoma.
• Document is under a permissive CC-BY-4.0 license for reuse.

Limitations

• Data scale is limited to a single case report (19.1 KB file).
• Column-level documentation and sample data are unavailable, limiting structured analysis.
• The report's findings are based on one patient, which may not be generalizable.

Provenance

Source

figshare, author JingJun Wang

Collection Method

Clinical case report and literature review.

Freshness

Last updated 2026-05-29 04:53:09