Ovine Hepatic Organoid Transcriptomic and Functional Data for Metabolism Studies

María-Cristina González-Montero developed ovine hepatic organoids from a male Assaf lamb. The dataset likely contains transcriptomic profiling results from RNA-seq and functional enrichment analyses, along with gene expression data from metabolic assays. The work was published on figshare in May 2026.

Use Cases

• Study nutrient-gene interactions based on transcriptomic profiling data
• Evaluate feed additive strategies based on metabolic response assays with DL-methionine and betaine
• Compare in vitro organoid models to native liver tissue based on comparative transcriptomic analysis

Strengths

• Dataset includes transcriptomic profiling via RNA-seq, a high-resolution method
• Functional validation includes gene expression analysis of key metabolic enzymes like CPT1A
• Data is licensed under CC-BY-4.0 for open reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset is small (851.5 KB), indicating limited scope

Provenance

Source

figshare

Collection Method

Organoids developed from progenitor cells of a male Assaf lamb, characterized by histology, immunofluorescence, and RNA-seq.

Freshness

Last updated 2026-05-11 04:27:33; freshness should be verified