Meta-Analysis of Menstrual Blood HPV Test Accuracy for Cervical Cancer Screening

Seven studies involving 1,672 adult women were included in this meta-analysis examining the diagnostic accuracy of self-collected menstrual blood for high-risk human papillomavirus testing. The analysis, conducted by Xuechao Ji in October-November 2024, reports pooled sensitivity and specificity estimates for detecting cervical intraepithelial neoplasia and cervical cancer. The dataset is a 282.9 KB DOCX file containing the systematic review and meta-analysis results.

Use Cases

• Benchmarking the performance of self-sampling HPV tests based on reported sensitivity and specificity metrics.
• Informing public health screening policy based on the meta-analysis of diagnostic accuracy evidence.
• Designing follow-up diagnostic studies based on the identified high sensitivity and low specificity of the method.

Strengths

• Includes data from 1,672 participants aggregated from seven studies.
• Reports specific pooled sensitivity (0.96) and specificity (0.53) estimates with 95% confidence intervals.
• Follows PRISMA guidelines for systematic review and uses bivariate random-effects and HSROC models for meta-analysis.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is a 282.9 KB DOCX document; data extraction is required for computational analysis.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of observational studies from PubMed, Embase, and Cochrane databases.

Time Range

Studies published through October 23, 2024; analysis conducted October-November 2024.

Freshness

Last updated 2026-04-21 17:44:02; freshness should be verified.

Geography

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