Human B-1 Lymphocyte Review and Phenotypic Data Table

A 3.5 MB document reviews the debated existence and characteristics of human B-1 lymphocytes, a subset of B cells with innate-like properties. Authored by Mónica Itzel Martínez-Gutiérrez and published under CC-BY-4.0, it was last updated in April 2026. The text critically examines phenotypic markers, tissue residency, and the functional equivalence of human B-1 cells to their murine counterparts.

Use Cases

• Literature review on human B-1 cell biology based on the detailed historical and functional discussion.
• Comparison of murine and human B-1 cell phenotypes based on described markers like CD19+ CD27+ CD43+.
• Analysis of B-1 cell tissue distribution based on mentions of blood, pleural cavities, spleen, and fetal tissues.
• Investigation of natural antibody specificities based on references to antibodies against phosphorylcholine or bacterial polysaccharides.

Strengths

• File size is 3.5 MB, indicating a substantive document.
• License is clearly defined as CC-BY-4.0, permitting broad reuse.
• Last update date is precisely recorded as 2026-04-13 04:35:43.

Limitations

• Row count and column definitions are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The primary content is a review article, which may contain summarized data rather than raw datasets.

Provenance

Source

figshare, author Mónica Itzel Martínez-Gutiérrez.

Collection Method

Likely contains a compiled literature review and associated data table.

Time Range

Covers research from the 1980s to the 2020s, focusing on a 2011 identification milestone.

Freshness

Last updated 2026-04-13 04:35:43; freshness should be verified.

Geography

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