Sepsis ICU Patient Biomarker Trajectories and Early Enteral Nutrition, 2011-2025

3,354 adult ICU patients with sepsis from West China Hospital form a retrospective cohort from 2011 to 2025. The dataset contains longitudinal patterns of albumin, lactate, and procalcitonin biomarkers analyzed with group-based trajectory modeling. It was authored by Jing Zhou and last updated in April 2026.

Use Cases

• Modeling patient risk stratification based on joint albumin, lactate, and procalcitonin trajectory patterns.
• Investigating associations between early enteral nutrition and metabolic-inflammatory biomarker responses.
• Predicting 28-day mortality risk using identified high-risk inflammatory surge trajectory groups.
• Training models to identify heterogeneous patient subgroups within sepsis populations.

Strengths

• Includes 3,354 patient records, providing a substantial cohort for analysis.
• Covers a 14-year time range from 2011 to 2025.
• Analyzes three key clinical biomarkers (albumin, lactate, procalcitonin) with longitudinal trajectory modeling.
• Results include specific statistical associations, such as an OR of 0.57 for EEN and high-risk class membership.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying data table is unknown, which may limit suitability assessment.
• Data reflects a single-center study from West China Hospital, which may limit generalizability.

Provenance

Source

figshare, authored by Jing Zhou.

Collection Method

Retrospective cohort study of ICU patients.

Time Range

2011 to 2025

Freshness

Last updated 2026-04-28 05:27:46; freshness should be verified.

Geography

West China Hospital