Clinical Trial Data on 5:2 Intermittent Fasting for Obese Women with PCOS

A 12-week non-randomized, single-arm interventional study of 90 obese women with polycystic ovary syndrome (PCOS). The dataset, authored by Wencheng An and last updated in March 2026, contains results on the effects of a 5:2 intermittent fasting diet with meal replacement on body weight, metabolic markers, and reproductive outcomes.

Use Cases

• Analyzing weight loss efficacy based on body weight and BMI changes reported in the results.
• Studying changes in insulin resistance based on HOMA-IR and glucose level metrics.
• Investigating correlations between metabolic improvement and menstrual regularity or ovulation frequency.
• Comparing intervention effects between meal replacement and non-meal replacement groups as described.

Strengths

• Study design utilized Propensity Score Matching (PSM) to control for baseline characteristics like age and BMI.
• Results report specific, statistically significant changes (e.g., weight reduced from 77.15 kg to 69.1 kg, P < 0.001).
• Clinical outcomes include both metabolic (HOMA-IR, glucose) and reproductive (menstrual regularity, ovulation) markers.

Limitations

• Dataset is very small at 22.6 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• The study is described as non-randomized and single-arm, which may limit causal inference.

Provenance

Source

figshare, author Wencheng An.

Collection Method

Data likely originates from a clinical interventional study, as described in the methods section.

Time Range

The intervention period was 12 weeks; specific study dates are not provided.

Freshness

Last updated 2026-03-18 05:34:40; freshness should be verified.