Clinical Trial Data on Tea Tree Oil vs. Chlorhexidine Mouthwash for Gingivitis

An exploratory randomized clinical trial compared a 1% tea tree oil mouthwash to 0.12% chlorhexidine in 30 adults with plaque-induced gingivitis. The dataset includes clinical indices, bacterial counts, and adverse effect measurements collected over a 15-day period. The study was authored by Alfred Menat and last updated in June 2026.

Use Cases

• Compare the efficacy of natural and chemical antimicrobial agents based on plaque and gingival index outcomes.
• Analyze the relationship between bacterial load reduction and mouthwash formulation based on reported bacterial counts.
• Evaluate the side effect profiles of oral care products based on documented adverse effects like taste alteration.
• Study dose-dependent patterns in essential oil formulations based on the described 1% TTO concentration.

Strengths

• Data originates from a triple-blind, randomized controlled trial, a strong study design.
• Includes results from 30 human participants, providing a basis for statistical analysis.
• Clinical outcomes (plaque/gingival indices, bacterial counts) are reported with statistical significance (p < 0.001).
• Dataset is openly licensed under CC-BY-4.0 for reuse.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• The dataset is very small at 36.6 KB, indicating limited scope.
• The geographic origin of the trial participants is not specified, which may limit generalizability.

Provenance

Source

figshare, authored by Alfred Menat.

Collection Method

Data collected from an exploratory randomized, controlled, triple-blind clinical trial.

Time Range

The study period covered 15 days of treatment.

Freshness

Last updated 2026-06-03 06:00:43; freshness should be verified.