Table 1_Effectiveness and safety of skull base-peripheral acupuncture for post-stroke cogn

Twenty-four randomized controlled trials involving 1,962 patients were analyzed to evaluate skull base-peripheral acupuncture for post-stroke cognitive impairment. The meta-analysis, conducted by Yinyi Xiong and published in 2026, found significant improvements in cognitive scores and activities of daily living compared to control groups. The review is registered with PROSPERO and includes data from eight databases searched up to July 2025.

Use Cases

• Assessing the efficacy of acupuncture for cognitive rehabilitation based on meta-analysis of clinical effective rate, MMSE, and MoCA scores.
• Evaluating treatment safety profiles for post-stroke interventions based on reported adverse event data.
• Investigating heterogeneity in treatment outcomes based on subgroup analyses of combination therapy and treatment duration.
• Informing clinical trial design for stroke rehabilitation based on methodological limitations identified in the review.

Strengths

• Analysis is based on 24 randomized controlled trials involving 1,962 patients, providing a substantial evidence base.
• Reports specific statistical outcomes including odds ratios and mean differences with confidence intervals for multiple cognitive and functional measures.
• Includes a PROSPERO registration identifier (CRD420251142773), indicating a pre-registered systematic review protocol.

Limitations

• The dataset is a 22.3 KB document; the underlying trial data are not provided, limiting direct analysis.
• Description metadata is limited; actual data quality requires manual inspection after download.
• The authors note methodological limitations, high heterogeneity, and potential publication bias in the included studies.

Provenance

Source

Yinyi Xiong via figshare.

Collection Method

Systematic review and meta-analysis of randomized controlled trials from eight Chinese and English databases.

Time Range

Trials from database inception to July 2025.

Freshness

Last updated 2026-04-30 04:21:13; freshness should be verified.