Table 1_Effectiveness of physical therapy for lower limb lymphedema in gynecological cancer survivors: a systematic review of randomized controlled trials.docx

This systematic review synthesizes evidence from 6 randomized controlled trials involving 289 patients. It evaluates the effectiveness of physical therapy interventions for secondary lower limb lymphedema in gynecological cancer survivors. The review assessed outcomes including limb volume, pain, physical function, and quality of life.

Use Cases

• Analyze the reported reductions in lower limb volume or circumference across the 6 included RCTs.
• Compare the effectiveness of multimodal versus single physical therapy modes on outcomes like pain and muscle strength.
• Assess the safety profile of interventions by reviewing data on mild and serious adverse events.
• Evaluate the methodological quality of included studies using the Cochrane Risk of Bias 2 (ROB 2) tool assessments.

Strengths

• Based on 6 randomized controlled trials, a gold-standard study design for evaluating interventions.
• Includes data from 289 eligible patients across the synthesized studies.
• Uses a systematic methodology with registration in PROSPERO (CRD420251274284) and the Cochrane ROB 2 tool for quality assessment.

Limitations

• The dataset is a 12.3 KB document summarizing findings, not the raw trial data, limiting direct analysis.
• Small overall evidence base with only 6 included trials, which may limit statistical power and generalizability.
• Potential for publication bias inherent in systematic reviews of published literature.

Provenance

Source

Systematic review conducted by author Yuancheng Wu, sourced from figshare.

Collection Method

Literature search across Medline, Web of Science, Scopus, and Cochrane Library; screening and data extraction performed on the Rayyan platform.

Time Range

Literature published up to 27 December 2025.

Freshness

Literature search includes studies published up to 27 December 2025; document last updated 2026-03-20.