Table 1_Effects of aging on host responses in gingival crevicular fluid in natural gingivi

A cross-sectional study of 40 patients with natural gingivitis, comparing inflammatory and tissue remodeling mediator levels in gingival crevicular fluid between young (18–35 years) and elder (36–75 years) cohorts. The dataset, authored by Yung-Ting Hsu and last updated in March 2026, includes measurements for 39 mediators such as MPO, IL-1β, IL-6, IL-8, MMP-8, MMP-9, and TIMP-1.

Use Cases

• Compare inflammatory mediator expression (e.g., MPO, IL-1β, IL-6, IL-8) between age groups based on the described immunoassay results.
• Analyze tissue remodeling capacity based on the ratios of MMP-8/TIMP-1 and MMP-9/TIMP-1 mentioned in the results.
• Investigate correlations between clinical attachment loss and specific cytokine levels in gingivitis patients.
• Model age as a factor in disease susceptibility and healing capacity in periodontal inflammation.

Strengths

• Includes data for 39 specific inflammatory and tissue remodeling mediators.
• Compares two distinct age cohorts (22 young and 18 elder patients) with statistical analysis (p-values) provided.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (20.8 KB), indicating limited scope.

Provenance

Source

figshare, author Yung-Ting Hsu.

Collection Method

Cross-sectional study using bead-based multiplex immunoassays on GCF samples.

Time Range

Study period not specified; data reflects a single cross-sectional snapshot.

Freshness

Last updated 2026-03-18 07:41:19; freshness should be verified.

Geography

Geographic coverage of patient recruitment is not specified.