Meta-Analysis of HIIT Effects on Glycemic Control in Adults with Prediabetes

Thirteen intervention studies are included in this systematic review and meta-analysis comparing high-intensity interval training (HIIT) to moderate-intensity continuous training (MICT) for adults with prediabetes. The work was authored by Jun Li and uploaded to figshare on 2026-05-14. It synthesizes findings on outcomes including fasting blood glucose, 2-hour plasma glucose, and cardiorespiratory fitness, with evidence certainty graded as low to very low.

Use Cases

• Compare the efficacy of HIIT versus MICT for improving fasting glucose based on the reported meta-analysis results.
• Assess the impact of HIIT on post-challenge glycemic control based on the 2-hour plasma glucose outcome.
• Evaluate the effect of exercise interventions on cardiorespiratory fitness in a prediabetic population based on the standardized mean difference reported.
• Identify research gaps for future clinical trials based on the review's conclusions about limited evidence for HbA1c and lipid outcomes.

Strengths

• The review is registered in PROSPERO (CRD42024605154), indicating a pre-defined protocol.
• It applies standardized assessment tools including Cochrane Risk of Bias 2 and GRADE for evidence certainty.
• The analysis provides specific effect sizes with confidence intervals for key outcomes like 2hPG and cardiorespiratory fitness.

Limitations

• The dataset is a 23.0 KB DOCX document, suggesting it contains summary text and tables rather than raw study data.
• Column-level documentation for any underlying data is absent; field semantics must be inferred from the text.
• The quantitative synthesis was limited, with no meta-analysis performed for comparisons with non-exercise controls due to a small number of eligible studies.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies from PubMed, Embase, Web of Science, EBSCO, and the Cochrane Library searched from inception to January 2026.

Time Range

Literature search covered studies from database inception to January 2026.

Freshness

Last updated 2026-05-14 04:25:21; freshness should be verified.