Effects of Kangfuxin on Periodontal and Masticatory Outcomes in 300 Periodontitis Patients

A retrospective cohort study of 300 chronic periodontitis patients receiving implant rehabilitation with adjunctive Kangfuxin solution. The dataset contains 6-month outcomes including probing depth, clinical attachment level, peri-implantitis incidence, marginal bone loss, bite force, mixing ability, and inflammatory biomarkers. The study was authored by Jiaqing Sun and covers patients treated between January 2019 and June 2024.

Use Cases

• Analyze the relationship between Kangfuxin exposure duration and periodontal parameter improvement based on the reported superior reduction in probing depth with prolonged use.
• Model peri-implantitis risk factors based on reported incidence rates and patient characteristics like severe periodontitis.
• Assess correlations between inflammatory biomarker levels (IL-1β, IL-6, TNF-α) and clinical outcomes like marginal bone loss.
• Evaluate the impact of adjunctive therapy on functional recovery based on reported improvements in bite force and mixing ability index.

Strengths

• Includes results for 300 patients with a mean age of 52.3 years and a gender breakdown (56% male).
• Reports specific 6-month outcome metrics with statistical significance (e.g., PD decreased from 4.8 mm to 3.4 mm, p < 0.001).
• Contains data on multiple outcome domains: clinical (PD, CAL), radiographic (MBL), functional (bite force, MAI), and biochemical (inflammatory biomarkers).
• Provides a historical benchmark comparison for peri-implantitis incidence (3.0% vs. 12%).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (16.0 KB), suggesting limited scope, likely a summary table rather than raw patient-level data.

Provenance

Source

figshare

Collection Method

Retrospective cohort study.

Time Range

January 2019 to June 2024

Freshness

Last updated 2026-04-23 04:20:24; freshness should be verified.

Geography

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