Meta-Analysis of Zingiberaceae Effects on Cognitive Outcomes in Adults

Desirée Victoria-Montesinos published a systematic review and meta-analysis on the effects of Zingiberaceae-derived interventions on cognitive outcomes in adults. The analysis includes 18 randomized, double-blind, placebo-controlled clinical trials sourced from databases like MEDLINE and Scopus up to March 2026. It reports a statistically significant improvement in memory-related outcomes.

Use Cases

• Assessing the efficacy of curcumin and ginger on memory based on pooled clinical trial results
• Evaluating domain-specific cognitive effects (executive function, global cognition) from Zingiberaceae interventions
• Informing the design of future clinical trials based on identified heterogeneity and risk of bias
• Synthesizing evidence on nutraceutical strategies for age-related cognitive decline

Strengths

• Includes 18 randomized, double-blind, placebo-controlled clinical trials
• Reports a standardized mean difference of 0.57 for memory-related outcomes with a 95% confidence interval
• Registered with PROSPERO (CRD420261325966), indicating a structured review process

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download
• Column-level documentation is absent; field semantics must be inferred after download
• Evidence is described as very uncertain due to substantial heterogeneity and a small number of studies

Provenance

Source

Desirée Victoria-Montesinos

Collection Method

Systematic review and meta-analysis of randomized controlled trials from MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, and Scopus.

Time Range

Trials from database inception to March 2026.

Freshness

Last updated 2026-05-11 04:25:56; freshness should be verified