Efficacy and Safety of ALA/MAL Photodynamic Therapy for Basal Cell Carcinoma

55 studies involving 2123 patients and 2995 lesions were included in this systematic review and meta-analysis. The dataset, authored by Meiyu Jiang and last updated in April 2026, compiles evidence on photodynamic therapy for superficial and nodular basal cell carcinoma, reporting pooled response, recurrence, and adverse event rates.

Use Cases

• Compare complete response rates between ALA-PDT and MAL-PDT for different BCC subtypes based on the reported meta-analysis results.
• Analyze factors contributing to heterogeneity in treatment outcomes based on mentioned subgroup analyses of study design and treatment parameters.
• Model recurrence rates for superficial and nodular BCC following photodynamic therapy based on the pooled statistics.
• Assess the cosmetic outcomes (beauty effect rate) of non-invasive skin cancer treatments based on the reported pooled rates.

Strengths

• Includes data from 55 eligible studies, providing a substantial evidence base.
• Reports specific pooled rates with confidence intervals for key outcomes like complete response (0.88 for sBCC, 0.75 for nBCC) and recurrence.
• Adhered to PRISMA 2020 guidelines, suggesting a structured methodological approach.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (25.5 KB), indicating limited raw data scope.

Provenance

Source

figshare, author Meiyu Jiang.

Collection Method

Systematic review and meta-analysis of literature from PubMed, Embase, Cochrane Library, and Web of Science up to December 31, 2025.

Time Range

Literature search covered studies up to December 31, 2025.

Freshness

Last updated 2026-04-14 05:36:34; freshness should be verified.

Geography

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