Table 1_Efficacy and safety of Ginkgo biloba leaf extract injection for vascular cognitive

Twenty-two randomized controlled trials involving 2,375 patients in China from 2005 to 2025 were analyzed. The meta-analysis evaluates the impact of Shuxuening injection on cognitive and neurological outcomes using standardized scales. Jingchao Miao published this systematic review on figshare in April 2026 under a CC-BY-4.0 license.

Use Cases

• Conducting a meta-analysis based on aggregated results from 22 randomized controlled trials.
• Evaluating treatment efficacy for vascular cognitive impairment based on Mini-Mental State Examination (MMSE) scores.
• Assessing neurological function changes based on National Institutes of Health Stroke Scale (NIHSS) data.
• Analyzing safety profiles based on reported adverse event incidence rates.
• Modeling treatment response rates based on the overall response rate metric.

Strengths

• Aggregates data from 22 trials with a total of 2,375 patients.
• Reports results with 95% confidence intervals for multiple clinical scales (MMSE, HDS, BI, NIHSS).
• Includes a systematic review registration identifier (CRD42024557472) for traceability.

Limitations

• All 22 trials were conducted in China, which may limit geographic generalizability.
• The certainty of evidence is noted as limited by methodological weaknesses in the original studies.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

Jingchao Miao via figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials from eight databases.

Time Range

Trials conducted between 2005 and 2025.

Freshness

Last updated 2026-04-13 05:44:09

Geography

China