Meta-Analysis of Stem Cell Therapy Efficacy for Sjögren's Syndrome Dry Eye

114 patient records from five studies are aggregated in this systematic review and meta-analysis. The dataset, authored by Jizhong Zhang and published in April 2026, quantifies changes in OSDI scores, Schirmer test results, and adverse event rates to evaluate stem cell therapy for dry eye syndrome caused by Sjögren's syndrome.

Use Cases

• Evaluate treatment efficacy based on OSDI score changes reported in the meta-analysis
• Analyze safety profiles based on adverse event rates like injection pain and ocular discomfort
• Compare outcomes across different time points based on mean difference results at 2 weeks, 4 months, and 12 months

Strengths

• Includes results from five studies involving 114 patients
• Provides specific efficacy metrics, such as a mean OSDI score change of -15.10
• Reports safety outcomes with incidence rates, like 14% for injection pain

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data may reflect temporal bias inherent to the literature review cutoff date of January 2026

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of literature from PubMed, Embase, and Cochrane Library

Time Range

Studies published prior to 16 January 2026

Freshness

Last updated 2026-04-29 05:57:18