Meta-Analysis of Intraovarian PRP Efficacy for Poor Ovarian Reserve

A meta-analysis of seven randomized controlled trials involving 422 women with poor ovarian reserve or ovarian insufficiency, published on figshare in 2026. The study, conducted by Yuan Fang, systematically reviewed the efficacy of intraovarian autologous platelet-rich plasma (PRP) on ovarian reserve markers and pregnancy rates. It includes aggregated results for parameters like anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), antral follicle count (AFC), and estradiol.

Use Cases

• Evaluating the effect of PRP on ovarian reserve markers like AMH and AFC based on the meta-analysis results
• Assessing changes in hormone levels such as FSH and estradiol following PRP treatment
• Comparing pregnancy outcomes between PRP and control groups in women with ovarian insufficiency

Strengths

• Analysis includes data from seven RCTs involving 422 participants
• Follows PRISMA guidelines and is registered in PROSPERO (CRD420251233432)
• Reports specific effect sizes with confidence intervals for key outcomes like AFC (MD = 0.81) and FSH (MD = -5.72)

Limitations

• The dataset is a 16.5 KB DOCX file containing only summary tables, not raw patient-level data
• Column-level documentation is absent; field semantics must be inferred after download
• The analysis notes limited number of studies and heterogeneity in treatment protocols

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials sourced from PubMed, Cochrane Central, Embase, CNKI, VIP, and Wanfang.

Time Range

Literature search conducted up to November 22, 2025.

Freshness

Last updated 2026-05-12 04:19:36