Review of Yeast Engineering for Sterol, Steroid, and Bile Acid Production

He Yeon Song authored a review document titled 'Engineering yeast for sustainable production of sterols, steroids, and bile acids: advances, strategies, and future directions'. The 1.7 MB document was uploaded to figshare on 2026-05-22 under a CC-BY-4.0 license. It discusses progress and bottlenecks in engineering Saccharomyces cerevisiae for producing sterols, steroids, and bile acids.

Use Cases

• Identify structural and regulatory bottlenecks in sterol and steroid metabolic pathways based on the review's discussion.
• Survey strategies for pathway rewiring and cofactor balancing in yeast based on the described advances.
• Investigate the challenges of reconstructing primary bile acid biosynthesis from cholesterol based on the highlighted hurdles.
• Explore applications of bile acid-producing yeast for studying host-microbiome signaling based on the review's concluding remarks.

Strengths

• Document is 1.7 MB, indicating a substantive text file.
• The review is recent, with a last updated date of 2026-05-22.
• The work is openly licensed under CC-BY-4.0.

Limitations

• The dataset is a single DOCX file; the underlying data or tables referenced are not provided as separate, machine-readable files.
• Row count and column-level documentation are absent; the content's structure must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Authored review document.

Freshness

Last updated 2026-05-22 06:10:15; freshness should be verified.