Multidrug-Resistant Organism Epidemiology in a Chinese Hospital Over 10 Years

2,669 adult inpatient records from a Chinese tertiary hospital reveal the overall MDRO detection rate increased from 36.9% to 56.4% during strict COVID-19 containment. The data covers hospital-acquired infections from 2013 to 2023, stratified into pre-pandemic, strict containment, and post-adjustment phases. Shanshan Yang authored this retrospective cohort study analyzing clinical and microbiological data.

Use Cases

• Analyze shifts in dominant resistant pathogens like CRAB and CRE across policy phases using detection rates and species prevalence data.
• Model associations between invasive procedures (mechanical ventilation, urinary catheter use) and specific MDRO infections using odds ratios.
• Identify patient risk factors (male sex, age≥60 years, prolonged hospitalization) for distinct MDRO infection patterns.
• Track changes in infection site distribution, such as bloodstream infection percentage increases from 24% to 32%.

Strengths

• Contains 2,669 adult inpatient records with culture-confirmed hospital-acquired infections.
• Provides 10-year temporal coverage from 2013 to 2023 across three distinct policy phases.
• Includes multivariate logistic regression results with specific odds ratios for risk factors.

Limitations

• Limited to a single Chinese tertiary hospital, reducing generalizability.
• Small dataset size (34.4 KB) indicates limited raw data or summary statistics only.
• Unknown column structure and sample data availability hinders direct analysis.

Provenance

Source

Retrospective cohort study by Shanshan Yang, published on figshare.

Collection Method

Analysis of clinical and microbiological data from hospital records, with MDROs defined per CLSI guidelines.

Time Range

2013 to 2023

Freshness

Data covers up to 2023, with the study last updated in April 2026.

Geography

A single Chinese tertiary hospital.