Evidence Map for Acupuncture and Moxibustion Trials in Dry Eye Disease, 319 Studies

From database inception to December 1, 2025, this evidence map synthesizes 319 randomized controlled trials on acupuncture and moxibustion for dry eye disease. The dataset, created by Qidi Liu and last updated in April 2026, presents study characteristics, interventions, outcome indicators, and quality assessments. It includes analysis of six traditional Chinese medicine syndrome types and 48 total intervention types.

Use Cases

• Assessing the distribution of outcome indicators based on the 13 identified categories, such as ocular surface health assessments.
• Analyzing the prevalence of specific traditional Chinese medicine syndrome types, such as liver-kidney yin deficiency which accounted for 54.55% of studies.
• Evaluating the methodological quality of existing trials based on Risk of Bias 2.0 assessments mentioned in the description.
• Identifying research gaps in intervention types based on the documented 17 monotherapies and 31 combination therapies.

Strengths

• Includes a substantial number of studies, with 319 randomized controlled trials analyzed.
• Provides a structured breakdown of interventions, detailing 48 total therapy types.
• Categorizes outcome indicators into 13 distinct groups for systematic review.

Limitations

• The methodological quality of the included literature is described as generally low.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying evidence map data is unknown, which may limit suitability assessment.

Provenance

Source

Studies were retrieved from China National Knowledge Infrastructure (CNKI), VIP Database, WanFang Data, China Biology Medicine disc (CBM), PubMed, Web of Science, Embase, and the Cochrane Library.

Collection Method

Systematic evidence mapping of randomized controlled trials, with methodological quality evaluated using the Risk of Bias 2.0 tool.

Time Range

From database inception to December 1, 2025.

Freshness

Last updated 2026-04-21 04:22:39; freshness should be verified.