Staphylococcal msrA Gene Evolution and Transmission Analysis

Davit Janelidze's dataset contains 601 complete staphylococcal msrA coding sequences retrieved from GenBank. It details 41 allelic variants, evolutionary analyses, and transmission pathways, last updated on 2026-04 22. The data is licensed under CC-BY-4.0.

Use Cases

• Analyzing nucleotide diversity and selection pressures on the msrA gene based on described metrics (π, dN-dS, Tajima's D).
• Mapping transmission pathways and recombination events between Staphylococcus species and other genera.
• Identifying conserved functional domains within the MsrA protein sequence.
• Studying the association of predominant msrA alleles with plasmids.
• Assessing linkage disequilibrium to understand the persistence of successful allelic variants.

Strengths

• Includes 601 complete coding sequences for detailed analysis.
• Identifies 41 allelic variants with five predominant alleles accounting for approximately 90% of sequences.
• Provides results from multiple evolutionary analyses (e.g., nucleotide diversity π ≈ 0.039–0.042, strong purifying selection).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect source bias inherent to sequences available in GenBank.

Provenance

Source

GenBank

Collection Method

Retrieved and analyzed 601 complete staphylococcal msrA coding sequences.

Time Range

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Freshness

Last updated 2026-04-22 05:35:03; freshness should be verified.

Geography

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