Exclusion Criteria in Neuropathic Pain Clinical Trials, 2012-2022

A systematic review of 161 primary clinical trial publications for neuropathic pain treatments published from 2012 to 2022. The analysis extracted data on the number, type, and frequency of exclusion criteria, patient flow metrics, and reporting quality. The dataset was created by Raymundo Salcedo and last updated in March 2026.

Use Cases

• Analyze patterns in exclusion criteria usage based on reported frequencies of medical comorbidity, age, and pain score exclusions.
• Assess reporting transparency in clinical trials based on the reported rates of screening and eligibility numbers.
• Study correlations between different exclusion criteria, such as between minimum pain duration and score requirements.
• Evaluate the potential impact of common exclusions, like psychological comorbidities, on trial generalizability.

Strengths

• Analysis is based on 161 primary clinical trial publications, providing a substantial sample.
• Includes specific metrics like a median of 5 exclusion criteria per study and eligibility rates of 67.9%.
• Clear temporal coverage from 2012 to 2022.

Limitations

• The underlying data is a DOCX document; column-level structure and raw data tables are not provided.
• Row count for any extracted data is unknown, which may limit suitability assessment.
• Data may reflect publication and reporting bias inherent to the systematic review's source material.

Provenance

Source

figshare, author Raymundo Salcedo.

Collection Method

Systematic review of published clinical trial studies.

Time Range

2012 to 2022

Freshness

Last updated 2026-03-18 06:42:16