Taraxacum mongolicum EVLP Effects on Non-Small Cell Lung Cancer Cell Lines

Wei Peng published a dataset on figshare in April 2026 detailing the antitumor effects of plant-derived extracellular vesicle-like particles (EVLPs). The data, stored in a 10.5 KB XLSX file, likely contains results from in vitro and in vivo experiments on A549 and H1975 cell lines, including measurements of cell viability, migration, invasion, and mitochondrial function. The dataset is licensed under CC-BY-4.0.

Use Cases

• Modeling the dose-response relationship of TM-EVLPs on cancer cell viability based on the described concentration-dependent effects.
• Analyzing the correlation between mitochondrial membrane potential depolarization and reduced ATP production in treated cells.
• Investigating the association between TM-EVLP treatment and changes in epithelial-mesenchymal transition markers like E-cadherin and N-cadherin.
• Validating in vivo tumor growth reduction against in vitro clonogenicity and proliferation assay results.

Strengths

• Dataset is associated with a detailed methodological description covering in vitro assays and an in vivo xenograft model.
• Specific experimental details are provided, such as the use of A549 and H1975 cell lines and oral TM-EVLP doses of 5–20 mg/kg over 15 days.
• File is small (10.5 KB), facilitating quick download and initial inspection.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Data likely generated from laboratory experiments involving nanoparticle isolation, cell culture assays, and animal models as described.

Freshness

Last updated 2026-04-17 05:21:37; freshness should be verified.