Family-wise ISA Resistance in Atlantic Salmon with Viral Load and Gene Expression Data

Forty families of North American Atlantic salmon were experimentally challenged with Infectious Salmon Anemia Virus (ISAV) to assess family-level survival and resistance. The dataset includes viral load measurements via RT-qPCR and host gene expression data from kidney, spleen, heart, and gill tissues, collected during early-onset, peak mortality, and resolution phases of disease. It was authored by Amber E. Johnston and last updated in May 2026.

Use Cases

• Identify genetic markers for disease resistance based on family-wise survival and mortality rates.
• Analyze the correlation between viral load in different organs and phenotypic disease resistance.
• Study differential gene expression patterns, particularly in the kidney, associated with early viral recognition.
• Evaluate the impact of selective breeding for growth and sea lice resistance on ISA disease outcomes.

Strengths

• Includes data from 40 distinct Atlantic salmon families, enabling family-level analysis.
• Contains multi-organ viral load and gene expression data from kidney, spleen, heart, and gill.
• Experimental design includes both injection and cohabitation challenge methods.
• Sampling covers multiple disease phases: early-onset, peak mortality, and resolution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (516.8 KB), indicating a limited scope of records.

Provenance

Source

figshare

Collection Method

Experimental challenge study with ISAV on Atlantic salmon, with viral load and gene expression analysis.

Freshness

Last updated 2026-05-20 05:44:22; freshness should be verified.

Geography

North American Atlantic salmon (likely farmed stock).