Table 1_Feasibility of integrating genetic risk and digital health tools for cardiovascula

120 adults aged 40–69 with metabolic syndrome were enrolled in a four-arm randomized controlled pilot study. The FitPreV study protocol, authored by Diego Maria Tona, assesses the feasibility of integrating polygenic risk scores and wearable health devices into primary cardiovascular prevention within the Italian National Health Service. Data collection occurred at baseline, 1, 6, and 12 months, with results expected to guide larger-scale effectiveness trials.

Use Cases

• Assessing recruitment and retention rates for digital health interventions based on the described feasibility indicators.
• Analyzing changes in lifestyle behaviors and lipid profiles based on the secondary outcomes measured over 12 months.
• Evaluating the acceptability and structural readiness of integrating genetic risk assessment into general practice settings.
• Comparing the impact of different intervention arms (standard counseling, plus WHD, plus PRS, or both) on cardiovascular risk scores.

Strengths

• Study protocol is clearly defined with a sample size of 120 participants and a 12-month follow-up period.
• Focuses on a specific population: adults aged 40–69 with metabolic syndrome and a 10-year CVD risk between 2.5% and 10%.
• Employs a randomized controlled trial design with four distinct intervention arms for comparative analysis.

Limitations

• Row count is unknown, which may limit suitability assessment for direct data analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 15.8 KB file size suggests the dataset is limited in scope, likely containing the study protocol document rather than extensive raw trial data.

Provenance

Source

Diego Maria Tona via figshare

Collection Method

Data collected as part of a pilot randomized controlled feasibility study (FitPreV).

Time Range

Data collection occurred at baseline, 1, 6, and 12 months (specific years not provided).

Freshness

Last updated 2026-05-29 06:18:26; freshness should be verified.

Geography

Study conducted within the Italian National Health Service (SSN).