E. coli Growth Dynamics Under Tetracycline Stress in Wastewater Effluent

437.9 KB of experimental data examines how filtered wastewater effluent affects Escherichia coli growth and antibiotic tolerance under tetracycline stress. The dataset contains results from growth assays and RNA sequencing, characterizing physiological and transcriptomic responses. No differences in minimum inhibitory concentration values were observed, indicating tolerance rather than heritable resistance.

Use Cases

• Analyze lag phase duration data to quantify growth advantage of wastewater-exposed E. coli under tetracycline stress.
• Correlate transcriptomic data on differentially expressed genes with observed growth dynamics to study adaptation mechanisms.
• Use growth assay data to model bacterial persistence in environments impacted by antibiotics and wastewater effluent.

Strengths

• Data is derived from controlled laboratory experiments combining growth assays and RNA sequencing.
• Results are specific to Escherichia coli, tetracycline antibiotic, and filtered wastewater effluent.
• Dataset is openly available under a CC BY 4.0 license.

Limitations

• Dataset size is 437.9 KB, indicating a limited scope likely from a single experimental study.
• Specific row and column counts, sample sizes, and detailed data structure are not provided in the input.
• Findings are specific to one bacterial species (E. coli) and one antibiotic (tetracycline), limiting generalizability.

Provenance

Source

figshare, authored by Alejandra R. Chavez.

Collection Method

Data generated from laboratory growth assays and RNA sequencing of E. coli cultures.

Time Range

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Freshness

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Geography

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