Gynecologic Laparoscopy PONV Risk Factors, 2430 Patients April 2021-May 2022

2430 patients undergoing gynecologic laparoscopic surgery were analyzed to measure the association between flurbiprofen-containing analgesia and postoperative nausea and vomiting. Jingru Chen published the retrospective case-control study in March 2026. Multivariable logistic regression, propensity score matching, and subgroup analyses were used to identify independent risk factors.

Use Cases

• Modeling risk factors for postoperative nausea and vomiting based on perioperative data extracted from electronic medical records.
• Analyzing the association between specific analgesic regimens (flurbiprofen-containing PCIA) and adverse outcomes.
• Investigating subgroup effects, such as elevated risk in patients over 60 years or those receiving hydromorphone-based PCIA.
• Comparing opioid consumption and PONV incidence between different patient-controlled intravenous analgesia protocols.

Strengths

• Dataset includes 2430 patient records from a defined time period (April 2021 through May 2022).
• Analysis employed multivariable logistic regression, propensity score matching, and subgroup analyses for robust findings.
• Results include specific metrics like adjusted odds ratio (1.414), confidence interval (1.042–1.918), and absolute risk difference (4.7%).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is retrospective and from a single institution, which may limit generalizability.

Provenance

Source

figshare

Collection Method

Perioperative data extracted from electronic medical records for a retrospective study.

Time Range

April 2021 through May 2022

Freshness

Last updated 2026-03-19 06:49:38; freshness should be verified.