Table 1_Functional MRI evidence of brain alterations in premenstrual dysphoric disorder: a

Kornelia Bartoszewicz authored a systematic review synthesizing evidence on functional brain alterations in Premenstrual Dysphoric Disorder (PMDD). The review analyzed data from 598 participants, including 294 PMDD patients and 304 healthy controls, sourced from functional magnetic resonance imaging (fMRI) studies. The document was last updated on 2026-06-04.

Use Cases

• Identify neural biomarkers for PMDD based on reported alterations in the salience, default mode, and executive control networks.
• Inform novel therapeutic strategies based on findings of decreased activation in the anterior cingulate cortex and dorsolateral prefrontal cortex.
• Guide hypothesis generation for future fMRI studies based on reported impairments in corticolimbic connectivity.
• Compare patient and control group brain activity patterns based on the aggregated data from 598 participants.

Strengths

• Includes data from 598 total participants, providing a substantial sample size for a systematic review.
• Compares 294 PMDD patients against 304 healthy controls, enabling a clear case-control analysis.
• Provides specific neuroanatomical findings, such as decreased activation in the anterior cingulate cortex and increased activation in the amygdala.

Limitations

• The dataset is a 16.9 KB DOCX file, indicating a limited scope primarily containing review text rather than raw data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare

Collection Method

Systematic review of existing fMRI studies.

Freshness

Last updated 2026-06-04 05:40:42; freshness should be verified.