Genomic and Functional Analysis of Stress-Responsive Prophages in Lactobacillus Helveticus

Six temperate bacteriophages were isolated from Trentingrana natural whey starters and their induction dynamics were studied under dairy processing stresses. The research by Andrea Mancini, last updated in April 2026, reveals a non-binary model of prophage activation influenced by heat, acid, and oxidative stress. Findings suggest these prophages may act as context-dependent modulators of starter culture stability rather than direct disruptors.

Use Cases

• Modeling prophage induction dynamics based on stress exposure conditions described in the study.
• Analyzing the functional role of bacteriophage genes in natural whey starter stability.
• Investigating the relationship between host physiological status and phage genome replication cycles.
• Studying microbial population turnover in traditional cheese production based on stress-responsive phage dynamics.

Strengths

• Data is associated with a specific, peer-reviewed research study on a defined microbial system.
• The dataset includes analysis of six distinct bacteriophages under four controlled stress conditions.
• It is shared under a permissive CC-BY-4.0 license for reuse.

Limitations

• The dataset is a 20.9 KB DOCX document, suggesting limited raw data or a summary report rather than a primary data table.
• Column-level documentation and sample data are unavailable, making direct computational analysis impossible without file inspection.
• Row count is unknown, which may limit suitability assessment for quantitative modeling.

Provenance

Source

figshare, author Andrea Mancini

Collection Method

Isolation and genomic/functional analysis of six temperate bacteriophages from Trentingrana natural whey starters.

Freshness

Last updated 2026-04-23 05:27:57

Geography

Associated with Trentingrana cheese production.