Lactococcus cremoris FBMS_5810 Genomic and Preclinical Evaluation

Ioanna Farmakioti's genomic and preclinical evaluation of the probiotic candidate Lactococcus cremoris FBMS_5810 includes strain-specific gene identification and in vivo mouse study results. The dataset, last updated April 29, 2026, integrates genomic characterization with preclinical safety and efficacy assessments. It provides a systematic approach for probiotic validation in molecular microbiology.

Use Cases

• Identify strain-specific genes for adhesion and colonization based on genomic analyses mentioned in the description
• Evaluate probiotic safety profiles based on the described preclinical evaluation framework
• Analyze gut microbiota modulation effects based on the reported changes in Muribaculaceae and Ruminococcaceae abundance
• Investigate intestinal gene expression changes linked to probiotic administration based on Tnf and Zo1 expression data

Strengths

• Dataset integrates genomic characterization with in vivo preclinical evaluation, providing a multi-faceted assessment
• Specific microbial families affected by the probiotic are named, including Muribaculaceae and Ruminococcaceae
• License is CC-BY-4.0, allowing for open reuse and modification

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset size is 15.6 KB, indicating a very limited scope of data

Provenance

Source

figshare

Collection Method

Genomic analysis and preclinical in vivo study in mice, likely from laboratory research.

Freshness

Last updated 2026-04-29 05:38:00; freshness should be verified