Atlantic Salmon Leukocyte Responses to β-Glucan Training

A 676.4 KB document from figshare, authored by Thinh Hoang Nhan and last updated in May 2026, describes experimental data on trained immunity in Atlantic salmon. The study investigates transcriptional, functional, and metabolic changes in head kidney leukocytes after training with β-glucan and secondary stimulation with homologous or heterologous stimuli.

Use Cases

• Analyze stimulus-dependent transcriptional responses based on gene expression data mentioned in the description
• Model trained immunity phenotypes based on phagocytic activity and cytokine response patterns
• Investigate metabolic regulation in immune cells based on glycolytic and mitochondrial oxidative activity indicators
• Compare homologous versus heterologous immune training effects based on secondary stimulation with β-glucan or LPS

Strengths

• The description provides a detailed experimental protocol involving β-glucan training, a 5-day resting period, and secondary stimulation
• Multiple cellular outputs were assessed, including phagocytic activity, reactive oxygen species, nitric oxide, lactate, and fumarate
• The dataset is openly licensed under CC-BY-4.0

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The primary data file is a DOCX document, which likely contains textual results rather than raw structured data tables

Provenance

Source

figshare

Collection Method

Experimental study on Atlantic salmon leukocytes.

Freshness

Last updated 2026-05-07 04:37:08; freshness should be verified