Table 1_Glymphatic Dysfunction and Neuroinflammation in FXTAS

A 15.8 KB document containing research data on Fragile X-associated tremor/ataxia syndrome (FXTAS). The study analyzed DTI-ALPS index data from 14 FXTAS participants and 25 controls, and gene expression data from postmortem brain tissue and skin fibroblasts of 3 FXTAS and 12 control individuals. The dataset was authored by Andrea Elias-Mas and last updated on May 28, 2026.

Use Cases

• Correlating glymphatic dysfunction measured by DTI-ALPS index with FXTAS diagnosis.
• Analyzing dysregulation of immune and inflammatory gene pathways in FXTAS brain tissue.
• Investigating aquaporin-mediated transport pathway activity in fibroblasts from FXTAS patients.
• Studying potential links between CGG repeat length and glymphatic system metrics.

Strengths

• Includes matched control groups for both DTI-ALPS (25 controls) and gene expression (12 controls) analyses.
• Combines in vivo neuroimaging data (DTI-ALPS) with postmortem gene expression data from brain tissue and fibroblasts.
• Data is associated with a specific, peer-reviewed research study with clear objectives and results.

Limitations

• The dataset is very small (15.8 KB), suggesting it contains summary results or a manuscript rather than raw, analyzable data tables.
• Column-level documentation is absent; field semantics must be inferred after download.
• Sample sizes for some analyses are small (e.g., 3 FXTAS brain tissue samples).

Provenance

Source

figshare

Collection Method

Research study analyzing DTI-ALPS index and performing Reactome gene expression analysis.

Freshness

Last updated 2026-05-28 06:20:48; freshness should be verified.