GPX2+ Tumor Cell and LGALS1+ B Cell Interactions in HBV-Positive HCC

Featuring molecular data from a single-cell analysis of Hepatitis B virus-positive hepatocellular carcinoma. It was authored by Liang Lin and last updated in March 2026. The specific row and column counts are unknown.

Use Cases

• Analyze the correlation between GPX2 expression and MYC or CD44 levels in tumor cells.
• Investigate the CCL26-CCR3 signaling axis for its role in recruiting and educating B cells.
• Examine the prevalence of the immunosuppressive LGALS1+ B cell state and its association with patient outcomes.
• Model the relationship between GPX2 overexpression and accelerated tumorigenesis in vivo.

Strengths

• Data originates from a published single-cell analysis study.
• The dataset is associated with specific molecular targets like GPX2, CCL26, and CCR3.
• It is licensed under CC BY 4.0 for open use.

Limitations

• The dataset is very small at 10.7 KB, indicating limited scope.
• Row and column counts are unknown, making it difficult to assess analytical depth.
• The data is focused on a specific cancer subtype (HBV-positive HCC), limiting generalizability.

Provenance

Source

figshare

Collection Method

Single-cell analysis from a research study.

Freshness

Last updated in March 2026.