Mouse Model Data on Fluvastatin, Gut Microbiota, and Endometriosis Progression

17.2 KB of tabular results from a mouse model study investigating the relationship between fluvastatin treatment, gut microbiota, and endometriosis. The data, authored by Huilin Yang and last updated in May 2026, likely contains measurements of lesion growth, inflammatory markers, and microbial abundance changes, including Akkermansia muciniphila. Findings suggest gut microbiota contributes to the drug's protective effects.

Use Cases

• Analyzing correlations between drug treatment and gut microbiota composition changes based on metagenomic sequencing results.
• Investigating the relationship between specific bacterial abundance (e.g., Akkermansia muciniphila) and disease progression metrics.
• Modeling the immunomodulatory effects of a statin drug based on cytokine expression and immune cell activation data.
• Comparing disease outcomes following interventions like fecal microbiota transplantation versus direct bacterial supplementation.

Strengths

• Data is from a controlled experimental study with multiple validation methods (histology, PCR, flow cytometry, sequencing).
• License is CC-BY-4.0, permitting open sharing and adaptation.
• Specific focus on a key bacterium, Akkermansia muciniphila, is highlighted in the results.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 17.2 KB file size indicates a very limited scope, likely containing summary results rather than raw experimental data.

Provenance

Source

figshare, author Huilin Yang.

Collection Method

Data generated from a mouse model of endometriosis, involving tissue transplantation, drug administration, and multi-omics analysis.

Time Range

Temporal coverage of the experimental study is not specified.

Freshness

Last updated 2026-05-14 08:05:28; freshness should be verified.

Geography

Spatial coverage is not specified; the study was conducted in a laboratory setting.