Helicobacter Pylori and Triglyceride Levels in 2024 Clinical Study

A 2024 cross-sectional study of 678 participants assessed the association between Helicobacter pylori infection and serum lipid levels. After 1:1 propensity score matching on sex, age, and BMI, the analysis compared 214 H. pylori-positive and 214 H. pylori-negative individuals. The study found H. pylori infection was independently associated with higher triglyceride levels after adjusting for covariates.

Use Cases

• Analyze the association between H. pylori infection status (DOB value ≥ 4‰) and triglyceride (TG) levels in a propensity score-matched cohort.
• Compare serum lipid profiles, including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), between H. pylori-positive and negative groups.
• Model the relationship between H. pylori infection and TG levels while controlling for covariates like age, sex, smoking, alcohol use, hypertension, and diabetes.
• Investigate demographic and clinical characteristics (e.g., BMI) as matching variables in a study of H. pylori and metabolic risk.

Strengths

• Data is derived from a clearly defined study of 678 participants who underwent both a 13C-urea breath test and a lipid profile test.
• Analysis uses a rigorous 1:1 propensity score matching method on key covariates (sex, age, BMI), resulting in 214 matched pairs for comparison.
• Findings are specific, reporting an independent association between H. pylori infection and triglyceride levels after adjusting for multiple confounders.

Limitations

• The dataset is very small in file size (17.8 KB), suggesting it contains summary results or a single table rather than the raw participant-level data.
• As a cross-sectional study from a single hospital in 2024, findings show association, not causation, and may have limited geographic generalizability.
• Specific column names, row counts for individual variables, and sample data are unavailable, limiting direct analytical utility.

Provenance

Source

Yu Zhou, published on figshare.

Collection Method

Clinical data collection from 678 participants at a hospital who underwent 13C-urea breath tests and lipid profile tests.

Time Range

2024.

Freshness

Data reflects a study conducted in 2024, with the record last updated in March 2026.

Geography

Hospital-based study; specific location unknown.