Table 1_Herbst and Twin Block appliances in Class II malocclusion management for children:

Seven randomized controlled trials with 548 participants compare the skeletal, dental, and soft tissue effects of Herbst and Twin Block appliances for managing Class II malocclusion in children. The meta-analysis, conducted by Franz Tito Coronel-Zubiate and registered with PROSPERO, calculates standardized mean differences for outcomes like mentolabial angle and molar relationship. The document was last updated in May 2026 and is shared under a CC-BY-4.0 license.

Use Cases

• Comparing treatment efficacy between Herbst and Twin Block appliances based on skeletal, dental, and soft tissue outcomes.
• Informing clinical decisions for Class II malocclusion management based on patient-specific factors like adherence and growth stage.
• Assessing the certainty of evidence for orthodontic interventions using GRADE methodology.
• Identifying research gaps in pediatric orthodontics by analyzing results from included RCTs.

Strengths

• The analysis is based on 7 RCTs with 548 participants, providing a quantitative evidence base.
• A rigorous methodology was employed, including risk-of-bias assessment with Cochrane RoB 2.0 and evidence grading with GRADE.
• The review protocol was pre-registered with PROSPERO (CRD420251011083), enhancing transparency.

Limitations

• The dataset is a 672 KB DOCX document; the underlying tabular meta-analysis data is not provided as a separate structured file.
• Row count for the primary data is unknown, which may limit suitability assessment for computational analysis.
• Column-level documentation for any extracted data is absent; field semantics must be inferred from the manuscript.

Provenance

Source

Systematic review and meta-analysis conducted by Franz Tito Coronel-Zubiate, published on figshare.

Collection Method

Literature search across PubMed, Scopus, Web of Science, Cochrane Library, and EMBASE up to January 30, 2025.

Time Range

Literature search covered studies with no date restrictions up to January 2025.

Freshness

Last updated 2026-05-15 07:47:34; freshness should be verified.