Hip Instability and Scoliosis in Children with Spinal Muscular Atrophy, UAE 2018-2023

Fifty-four children with types 1–3 spinal muscular atrophy were included in this single-center retrospective study from the United Arab Emirates. The research, published on figshare under CC-BY-4.0, assessed the prevalence and severity of hip dislocation/subluxation and its association with scoliosis and SMN2 copy numbers. Hip dislocation in both hips was most prevalent in type 1 SMA patients, while fewer SMN2 copies correlated with a higher likelihood of scoliosis.

Use Cases

• Analyzing the prevalence of hip dislocation/subluxation based on SMA type and motor status.
• Investigating correlations between scoliosis presence and genetic factors like SMN2 copy number.
• Studying associations between patient demographics (gender, age) and hip abnormalities for screening program development.

Strengths

• Includes 54 patient records with a genetic diagnosis of SMA.
• Covers a 5-year time range from 2018 to 2023.
• Explicitly analyzes multiple clinical factors: SMA type, motor status, hip subluxation/dislocation, scoliosis, and SMN2 copies.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single center in the UAE, which may limit geographic generalizability.

Provenance

Source

figshare, author Hagir Al-Dulaimi.

Collection Method

Retrospective cross-sectional study of medical records.

Time Range

2018 to 2023

Freshness

Last updated 2026-04-20 05:23:15; freshness should be verified.

Geography

United Arab Emirates (single tertiary care center)