Systematic Review of Adolescent Cannabis Use and Brain Development, 2000-2025

A systematic review document analyzing neurodevelopmental consequences of adolescent cannabis use. The review screened 3,421 records and included 36 studies involving 8,432 participants, published by Valerio Ricci on figshare in April 2026. It examines structural brain changes, cognitive impacts, addiction vulnerability, and long-term outcomes.

Use Cases

• Meta-analysis of dose-dependent brain volume alterations based on neuroimaging findings mentioned in the description.
• Assessing elevated addiction risk (ORs 3.9–7.2) in adolescents versus adults based on epidemiological data.
• Evaluating methodological limitations for causal inference based on the discussion of confounders and observational designs.
• Informing age-specific prevention strategies based on conclusions about greater adolescent vulnerability.

Strengths

• Follows PRISMA guidelines for systematic review methodology.
• Includes data from 36 studies with 8,432 participants, providing a substantial evidence base.
• Covers a 25-year literature span (2000-2025) from multiple databases (PubMed, EMBASE, PsycINFO, Web of Science).

Limitations

• The dataset is a 33.7 KB DOCX document, which is a very small text file containing a review summary, not raw research data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Causal relationships for long-term outcomes are noted as unclear in the description due to methodological limitations.

Provenance

Source

figshare

Collection Method

Systematic literature review following PRISMA guidelines.

Time Range

Studies published between 2000 and 2025.

Freshness

Last updated 2026-04 27 05:16:29

Geography

Global (studies included are from international sources).