Immune and IgG Profiles in 696 Oral Lichen Planus Patients

696 patients with oral lichen planus were enrolled in a retrospective cross-sectional study. Peripheral lymphocyte subsets were quantified by flow cytometry, and serum levels of food-specific IgG antibodies against 14 antigens and inflammatory mediators were measured by ELISA. The dataset was authored by Yanjie Yang and last updated on May 11, 2026.

Use Cases

• Identify high-risk patient phenotypes based on combined immune-suppressed and IgG-positive status.
• Investigate associations between specific lymphocyte subsets and erosive disease severity.
• Analyze correlations between food-specific IgG positivity and inflammatory biomarker levels.
• Model the 'Two-Hit' pathogenic model linking T-cell deficiency and humoral responses.

Strengths

• Includes data from 696 patients, providing a substantial sample size.
• Measures multiple immune cell types (CD3+, CD4+, CD8+, CD19+, NK cells) and 14 food-specific IgG antigens.
• Stratifies patients by clinical type (erosive vs. non-erosive), gender, and age.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small at 25.5 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Retrospective cross-sectional study using flow cytometry and ELISA.

Freshness

Last updated 2026-05-11 05:28:38; freshness should be verified.