Immunological Profiles of Children with Autism and Atopic Dermatitis, 72 Subjects

A dataset of immunological markers for 72 children aged 1–11 years with autism spectrum disorder (ASD), comparing those with and without comorbid atopic dermatitis (AD). The data includes T and B lymphocyte subsets, immunoglobulins, cytokines, and blood cell counts, collected from a single-center cross-sectional study at Peking Union Medical Hospital from April 2019 to September 2025. The study was authored by Huijing Shi and published on figshare under a CC-BY-4.0 license.

Use Cases

• Analyze correlations between immune markers and ASD symptom severity based on measured T cell subsets and immunoglobulins.
• Investigate the moderating effect of atopic dermatitis on immune-symptom relationships using the described logistic regression framework.
• Compare allergic and inflammatory phenotypes between ASD subgroups based on levels of IgE, eosinophils, and IgG subclasses.
• Study immune homeostasis imbalance in pediatric neurodevelopmental disorders using the panel of measured immunological markers.

Strengths

• Includes data for 72 pediatric subjects with clear group stratification (42 without AD, 30 with AD).
• Measures a detailed immunological profile including lymphocyte subsets, immunoglobulins, cytokines, and complete blood count.
• Links clinical symptom scores (e.g., picky eating, sleep disturbances) to quantitative immune markers.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single-center study, which may limit generalizability.

Provenance

Source

figshare, authored by Huijing Shi.

Collection Method

Single-center cross-sectional study with clinical and laboratory measurements.

Time Range

Data collected from April 2019 to September 2025.

Freshness

Last updated 2026-04-10 05:58:09; freshness should be verified.

Geography

Study conducted at Peking Union Medical Hospital (PUMCH), location not specified.